v7.5 [Aug 26, 2015]
PTM Profiling
- A tool to compare and quantify detected modifications sites on proteins. Determines the protein's PTM changes by comparing the “area-under-the-curve” from the LC-MS of the modified peptide features to the associated, unmodified (native) peptide features.
Peptide Mapping
- A powerful comparison tool, which provides an intensity map of all the peptides associated with any particular protein ID. The maps can be analyzed in terms of the retention time vs intensity, or the peptide mass vs intensity. PEAKS allows users to compare peptide maps of up to 3 different data files.
Peptide Feature Intensity
- One button to fully analyze and quantitate peptides across all samples.
Automated Multi-Round Search
- A tool to launch multiple rounds of a database search using de novo only spectra.
- De novo only spectra are high quality spectra with high scoring de novo results that could not be identified in the initial database search.
More Friendly User Interface
- Direct link from peptide view/de novo view to LC/MS view
- Save preferred PTM list for PEAKS PTM search
- PEAKS can run smoothly under different language settings
- Spectrum viewer can run more smoothly
- Report more error messages when fails to open a PEAKS project
Algorithm Improvement
- Improved speed of inChorus search on large data set
- Improved feature detection efficiency for Waters QTOF data
Vendor Support
- Bundles Thermo MSFileReader 3.0 SP3 with PEAKS. MSFileReader can be installed during PEAKS installation. The Config Wizard can also install the MSFileReader
- Waters RAW data can be loaded in PEAKS out of the box. No further configuration is required
- Fixed an issue in Agilent data loading
Bugs Fixed
- Export all results from project when SPIDER has zero score hits
- Empty inChorus run without PEAKS DB
- Fail to load MZML file when empty peak list exists in file.
Enjoy the peaceful atmosphere of a lovely summer day with Summer Tri-Peaks.